A Happy 3′ Ending to the piRNA Maturation Story

نویسندگان

  • Benjamin Czech
  • Gregory J. Hannon
چکیده

For a decade, mystery has surrounded the mechanisms by which piRNA biogenesis yields distinct size classes of small RNAs within individual PIWI proteins. In this issue of Cell, two studies shed light on this process, identifying conserved PARN-family exonucleases that trim piRNAs to their mature size in silkworms and C. elegans.

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عنوان ژورنال:
  • Cell

دوره 164  شماره 

صفحات  -

تاریخ انتشار 2016